Phenibut Free Amino Acid – Powder, 50 grams

Phenibut Free Amino Acid – Powder, 50 grams

This premium, laboratory-grade research compound delivers ultra-pure raw Phenibut (4-Amino-3-phenylbutyric acid) free amino acid powder at ≥99%+ purity, representing the highest standard for modern scientific investigations into GABA-B receptor agonism and neurochemical modulation mechanisms in anxiety and cognitive enhancement. The lyophilized crystalline powder form provides investigators with a single-compound reference standard ideal for analytical testing, in vitro cell culture modeling of GABAergic pathways, and in vivo preclinical research applications where precise Phenibut administration is critical for studying anxiety reduction, neuroprotection, cognitive enhancement, and sleep quality improvement.

Phenibut is a phenylated derivative of GABA (gamma-aminobutyric acid) that crosses the blood-brain barrier more effectively than plain GABA due to the addition of a phenyl group, which enhances lipophilicity and neuronal uptake. This chemical modification distinguishes it from native GABA and contributes to its enhanced CNS bioavailability.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

• Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

• Formulation contains zero flow agents, excipients, or adulterants—pure Phenibut free amino acid only

• Strategic over-weighing compensates for powder adhesion loss, guaranteeing minimum 50g recoverable material

• PET single-wall jar features UV-resistant construction and tamper-proof seal for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

GABA-B Receptor Agonism & Anxiety/Cognitive Enhancement Profiling

Phenibut (4-Amino-3-phenylbutyric acid, NSC-10158, β-phenyl-GABA) functions as a GABA-B (beta-gamma-aminobutyric acid) receptor agonist, confirming its primary mechanism of action as a GABAergic pathway activator. The compound is a phenylated derivative of GABA (gamma-aminobutyric acid) that crosses the blood-brain barrier more effectively than plain GABA due to the addition of a phenyl group, which enhances lipophilicity and neuronal uptake, distinguishing it from native GABA and contributing to enhanced CNS bioavailability. Phenibut interacts with GABAergic neurotransmission pathways by binding to GABA-B receptors and modulating neuronal excitability, demonstrating comprehensive GABAergic system modulation. This unique mechanism positions Phenibut as a critical tool compound for investigating anxiety reduction and stress relief research, enhanced relaxation without sedation studies, improved cognitive function and mental clarity pathways, support for mood enhancement models, neuroprotective effects, sleep quality improvement, and GABAergic neurotransmission in preclinical models, offering potential therapeutic insights for anxiety and cognitive enhancement with enhanced blood-brain barrier penetration properties. Phenibut has been used in Russia since the 1960s for treating anxiety, insomnia, and asthenic conditions, demonstrating historical therapeutic relevance for anxiety and sleep disorders. Phenibut was developed by Soviet scientists for space physicians to help cosmonauts cope with stress, confirming specific therapeutic application for stress management and CNS protection.

Handling & Storage Guidelines

• Long-Term Storage: Store at room temperature, tightly sealed, away from heat, light and moisture; store in a cool and dry place. Protect from light and moisture; PET single-wall jar provides UV resistance to minimize degradation; keep tightly sealed; shelf life 36 months when stored properly

• Solubility: Soluble in water and ethanol; pH (1% solution): 6.0–7.0; dissolve by stirring; aqueous solutions are stable

• Appearance: White crystalline powder; clear solutions in water and ethanol when properly dissolved

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.