ACP-105 – Powder, 1g

ACP-105 – Powder, 1g

This premium, laboratory-grade research compound delivers ultra-pure raw ACP-105 powder at 99%+ purity, representing the highest standard for modern scientific investigations into selective androgen receptor modulation and tissue-specific anabolic signaling mechanisms. The lyophilized crystalline powder form provides investigators with a single-compound reference standard ideal for analytical testing, in vitro cell culture modeling of AR-positive tissues, and in vivo preclinical research applications where precise SARM isolation is critical for studying beneficial anabolic effects with reduced side effects compared to traditional androgen therapies.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

• Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

• Formulation contains zero adulterants, excipients, flow agents, or contaminants—pure ACP-105 only

• Strategic over-weighing compensates for powder adhesion loss, guaranteeing minimum 1g recoverable material

• PET single-wall jar features UV-resistant construction and tamper-proof seal for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

Selective Androgen Receptor Activation & Tissue-Specific Anabolic Profiling

ACP-105 functions as a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with high-affinity binding to the androgen receptor, demonstrating pEC50 values of 9.0 and 9.3 for AR wild type and T877A mutant respectively in cell-based functional assays. The compound exhibits partial agonist activity relative to natural testosterone while demonstrating remarkable tissue selectivity, producing strong anabolic effects in muscle tissue while showing reduced activity in prostate and seminal vesicle tissues, confirming its SARM profile with a better safety profile than traditional androgen therapies. ACP-105 is orally available and undergoes extensive metabolism, producing 19 different metabolites after oral administration with a 5.0-hour half-life in human hepatocytes. Unique to ACP-105 is its investigation for potential use in treating age-related cognitive decline; the drug has been found to reduce anxiety-like behavior in mouse models of Alzheimer’s disease when administered alone and enhances spatial memory when coadministered with the selective estrogen receptor β agonist AC-186. This tissue-selective mechanism positions ACP-105 as a critical tool compound for investigating sarcopenia mechanisms, osteoporosis treatment pathways, Alzheimer’s disease research, age-related cognitive decline models, and muscle wasting conditions in preclinical studies, offering potential therapeutic benefits without traditional androgen side effects.

Handling & Storage Guidelines

• Long-Term Storage: Powder: -20°C for 3 years; In solvent: -80°C for 1 year. Store desiccated in airtight conditions under inert gas; protect from light and moisture

• Solubility: DMSO: 60 mg/mL (206.33 mM), sonication recommended; Ethanol: 60 mg/mL (206.33 mM), sonication recommended; insoluble in aqueous buffers without surfactant

• Appearance: Fine white to off-white crystalline powder

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.