Fladrafinil (CRL-40,941) – Solution, 3000mg (100mg/mL)

Fladrafinil (CRL-40,941) – Solution, 3000mg (100mg/mL)

This premium laboratory-grade research compound is supplied as a ready-to-use analytical solution (100mg/mL in DMSO), engineered for modern scientific investigations requiring precise eugeroic (wakefulness-promoting) pharmacology. Fladrafinil demonstrates enhanced potency compared to parent adrafinil—purportedly 3 to 4 times more potent—due to its unique bis(p-fluoro) ring substitution, making it a valuable tool for in vitro/in vivo modeling of alertness pathways, cognitive endurance studies, fatigue resistance research, and behavioral regulation under stress.

All domestic orders ship directly from primary United States production facilities, ensuring rapid delivery to all 50 U.S. states. International orders to the UK and continental Europe are fulfilled through our dedicated United Kingdom shipping hub, enabling seamless, efficient customs clearance across European borders without delay.

• Lot-coded containers with publicly accessible third-party HPLC/MS lab reports verifying assay (dried basis) 98.0–102% for absolute transparency

• Formulation completely free of adulterants, excipients, and stabilizers to guarantee raw chemical purity in solution

• Strategic over-weighing inside the vial compensates for natural adhesion loss during laboratory transfer and pipetting

• Packaging engineering utilizes a light-protected glass vial with chemically inert tamper-proof seal to maintain solution stability during transit

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

Eugeroic Wakefulness-Promoting Agent Profile

Fladrafinil (CRL-40,941, fluorafinil) functions as a potent eugeroic wakefulness-promoting agent structurally related to modafinil and adrafinil, characterized as the bis(p-fluoro) ring-substituted derivative of adrafinil. Research indicates fladrafinil is purportedly 3 to 4 times more potent than adrafinil in wakefulness promotion, may indirectly enhance dopaminergic signaling to promote motivated behavior and sustained attention, elevate adrenergic tone supporting mental alertness while reducing fatigue perception, and exhibits distinct antiaggressive effects in animals which adrafinil does not produce. Its pharmacokinetic profile demonstrates higher bioavailability and longer active duration compared to adrafinil, making it ideal for extended wakefulness studies, cognitive endurance experiments, fatigue modeling, performance optimization under stress, executive function research, and behavioral regulation experiments involving impulsivity and emotional control.

Handling & Storage Guidelines

• Long-Term Storage: Store refrigerated at 4°C or frozen at -20°C in DMSO solution; protect from moisture and direct light; solution stable for up to 2 weeks at -20°C

• Solubility: Supplied pre-dissolved in DMSO at 100mg/mL; highly soluble in DMSO

• Appearance: Clear liquid solution in light-protected glass vial

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.