HMB-Ca – Powder, 100g

$14.99

HMB-Ca (THC-Free) – Powder, 100g is ultra-pure, analytical-grade β-hydroxy-β-methylbutyrate calcium salt powder containing 99%+ purity, designed for in vitro/in vivo muscle protein synthesis research and analytical testing. This lyophilized material activates the mTOR protein synthesis pathway and reduces muscle protein degradation via inhibition of ubiquitin-proteasome system activity, making it invaluable for investigators studying skeletal muscle metabolism, sarcopenia models, and exercise-induced hypertrophy mechanisms. Available for fast, compliant shipping to all U.S. states and European countries via dedicated logistics hubs.

  • Third-party certified lot coding with publicly available COA (Certificate of Analysis) for absolute purity transparency

  • Formulation completely free of adulterants, excipients, flow agents, and other compounds to guarantee raw chemical purity

  • Precision over-weighed by 5-10% inside vessel to compensate for natural adhesion loss during laboratory powder transfer

  • UV-resistant PET single-wall jar with tamper-proof seal engineered for transit safety and chemical stability

    HMB-Ca (THC-Free) – Powder, 100g is ultra-pure, analytical-grade β-hydroxy-β-methylbutyrate calcium salt powder containing 99%+ purity, designed for in vitro/in vivo muscle protein synthesis research and analytical testing. This lyophilized material activates the mTOR protein synthesis pathway and reduces muscle protein degradation via inhibition of ubiquitin-proteasome system activity, making it invaluable for investigators studying skeletal muscle metabolism, sarcopenia models, and exercise-induced hypertrophy mechanisms. Available for fast, compliant shipping to all U.S. states and European countries via dedicated logistics hubs.

    • Third-party certified lot coding with publicly available COA (Certificate of Analysis) for absolute purity transparency

    • Formulation completely free of adulterants, excipients, flow agents, and other compounds to guarantee raw chemical purity

    • Precision over-weighed by 5-10% inside vessel to compensate for natural adhesion loss during laboratory powder transfer

    • UV-resistant PET single-wall jar with tamper-proof seal engineered for transit safety and chemical stability

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Description

HMB-Ca – Powder, 100g

This premium, laboratory-grade research compound delivers ultra-pure raw β-hydroxy-β-methylbutyrate calcium salt powder at 99%+ purity, representing the highest standard for modern scientific investigations into muscle protein metabolism and anabolic signaling mechanisms. The lyophilized crystalline powder form provides investigators with a single-compound reference standard ideal for analytical testing, in vitro cell culture modeling of myotubes, and in vivo preclinical research applications where precise HMB isolation is critical for studying muscle catabolism reduction and protein synthesis enhancement.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

  • Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

  • Formulation contains zero adulterants, excipients, flow agents, or contaminants—pure HMB-Ca only

  • Strategic over-weighing compensates for powder adhesion loss, guaranteeing minimum 100g recoverable material

  • PET single-wall jar features UV-resistant construction and tamper-proof seal for transit safety


Technical Specifications & Chemical Profile

Chemical Property Specification Data
Product Name HMB-Ca – Powder, 100g
Common Synonyms Calcium HMB, β-Hydroxy-β-Methylbutyrate Calcium, Ca-HMB, Hydroxymethylbutyrate Calcium, Leucine Metabolite HMB
CAS Number 156999-69-8
Molecular Formula C₆H₁₃CaO₄⁻ (monohydrate: C₆H₁₄CaO₅)
Molar Mass 192.25 g/mol (anhydrous); 210.27 g/mol (monohydrate)
Primary Target Mechanism mTOR pathway activation; protein synthesis enhancement via ribosomal biogenesis; ubiquitin-proteasome system inhibition; reduced muscle protein catabolism; Akt/PKB signaling modulation; reduced caspase-3 activity
Physical Form Fine white to off-white crystalline powder (lyophilized, chalky)

Research Applications & Storage Protocols

mTOR Activation & Muscle Protein Synthesis Modulation Profile

HMB-Ca functions as a potent metabolite of the essential amino acid leucine, directly activating the mTOR (mechanistic target of rapamycin) pathway to stimulate ribosomal biogenesis and enhance muscle protein synthesis rates in in vitro myotube models. The compound inhibits the ubiquitin-proteasome system—the primary pathway for muscle protein degradation—by reducing caspase-3 activity and proteasome expression, thereby significantly decreasing muscle catabolism. HMB-Ca also modulates Akt/PKB signaling to promote anabolic conditions and has been shown to enhance wound healing through increased collagen deposition and fibroblast proliferation. These multi-target mechanisms position HMB-Ca as a critical tool compound for investigating sarcopenia mechanisms, exercise-induced hypertrophy research, age-related muscle loss models, HIV/AIDS-associated muscle wasting studies, and traumatic injury recovery pathways in preclinical models.

Handling & Storage Guidelines

  • Long-Term Storage: Store desiccated at room temperature (15-25°C) in airtight conditions; avoid moisture exposure and high humidity environments

  • Solubility: Soluble in water (moderate, ~10-20 mg/mL), DMSO (high); slightly soluble in ethanol; forms clear solutions in aqueous buffers

  • Appearance: Fine white to off-white chalky crystalline powder with dry, bitter, slightly unpleasant taste and nondescript/chalky odor

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.

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