NACET (N-Acetyl-L-Cysteine Ethyl Ester) – Powder, 5g

NACET (N-Acetyl-L-Cysteine Ethyl Ester) – 5g Powder

This premium laboratory-grade research compound delivers ultra-pure raw powder form with ≥98% purity verified by analytical testing. NACET represents a lipophilic prodrug for N-acetylcysteine and subsequently glutathione, offering technical value to modern scientific investigators studying antioxidant effects, glutathione (GSH) levels modulation, neuroprotection, retinal cell protection, diabetic retinopathy treatment, oxidative stress reduction, and anti-inflammatory activity in in vitro/in vivo modeling research application.

We proudly fulfill all U.S. orders directly from primary United States production facilities for domestic speed, while European and international orders utilize our dedicated United Kingdom shipping hub to ensure seamless, efficient customs clearance across the UK and continental Europe throughout all 50 U.S. states and European countries.

• Lot-coded material with public third-party lab reports providing absolute transparency for every batch

• Zero adulterants, excipients, or flow agents guarantee raw chemical purity for investigators

• Precision over-weighing compensates for natural adhesion loss during laboratory transfer procedures

• Double-sealed moisture barrier mylar bag with UV-resistant packaging engineered for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

Lipophilic Glutathione Prodrug & Antioxidant Activity Profile

N-Acetylcysteine ethyl ester (NACET, NAC-Et) is an antioxidant which acts as a lipophilic prodrug for N-acetylcysteine and subsequently glutathione, with improved bioavailability over N-acetylcysteine itself. The additional ethyl ester group enhances cellular uptake and bioavailability compared to N-acetylcysteine (NAC). NACET is best-known for its ability to improve intracellular glutathione levels and has fascinating antioxidant properties to help support healthy ageing. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. NACET has been researched in animal studies as a potential treatment for diabetic retinopathy, where its antioxidant effects are potent in the eyes, protecting retinal cells against oxidative damage. It has also been sold as a “dietary supplement” in combination with glycine under the name GlyNAC-Et as a supposedly improved version of the older glycine-NAC combination GlyNAC, which has been claimed to show efficacy in counteracting symptoms associated with aging as well as HIV infection, diabetes and nerve damage for in vitro/inivo modeling applications. NACET can be used in sports nutrition supplements to reduce oxidative stress after exercise and aid in body recovery.

Handling & Storage Guidelines

• Long-Term Storage: Store at room temperature; keep container tightly sealed, away from heat, light and moisture; minimize open air exposure; store in cool and dry place; keep in desiccated conditions

• Solubility: Soluble in water, hot Isopropyl alcohol, methyl acetate, and ethyl acetate; suitable for analytical testing and research application

• Appearance: White crystalline powder with pungent odor; off-white color in some formulations

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.