Phenibut HCl – Solution, 3000mg (100mg/mL)

Phenibut HCl – Solution, 3000mg (100mg/mL)

This premium, laboratory-grade research compound delivers ultra-pure Phenibut hydrochloride (HCl) solution at 100mg/mL concentration in optimized PEG400 vehicle, representing the highest standard for modern scientific investigations into GABA-B receptor agonism and neurochemical modulation mechanisms in anxiety and cognitive enhancement. The ready-to-use solution format eliminates preparation time and ensures precise dosing accuracy for in vivo animal studies, eliminating solubility variability and providing investigators with a validated vehicle system ideal for analytical testing, pharmacokinetic modeling, and in vivo preclinical research applications where precise Phenibut HCl administration is critical for studying anxiety reduction, neuroprotection, cognitive enhancement, and sleep quality improvement.

Phenibut HCl is the hydrochloride salt form of Phenibut (4-Amino-3-phenylbutyric acid), which offers enhanced stability and solubility compared to the free acid form. The solution utilizes PEG400 as the solvent vehicle, which provides excellent solubility and bioavailability for oral and injectable research applications.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

• Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

• Formulation contains PEG400 with 100mg/mL Phenibut HCl (≥99% purity) – less than 10% variance for consistency

• Strategic over-fill compensates for solution adhesion loss, guaranteeing minimum 30mL (3000mg) recoverable volume

• Glass bottle features UV resistance and tamper-proof seal for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

GABA-B Receptor Agonism & Anxiety/Cognitive Enhancement Profiling

Phenibut HCl (γ-Amino-β-phenylbutyric Acid, β-phenyl-γ-Aminobutyric Acid, β-phenyl-GABA, Fenibut) functions as a GABA-B (beta-gamma-aminobutyric acid) receptor agonist, confirming its primary mechanism of action as a GABAergic pathway activator. The compound is a GABA mimetic that acts as an agonist at GABAB receptors, demonstrating comprehensive GABAergic system modulation. It is a phenylated derivative of GABA (gamma-aminobutyric acid) that crosses the blood-brain barrier more effectively than plain GABA due to the addition of a phenyl group, which enhances lipophilicity and neuronal uptake, distinguishing it from native GABA and contributing to enhanced CNS bioavailability. Phenibut HCl interacts with GABAergic neurotransmission pathways by binding to GABA-B receptors and modulating neuronal excitability, demonstrating comprehensive GABAergic system modulation. This unique mechanism positions Phenibut HCl solution as a critical tool compound for investigating anxiety reduction and stress relief research, enhanced relaxation without sedation studies, improved cognitive function and mental clarity pathways, support for mood enhancement models, neuroprotective effects, sleep quality improvement, and GABAergic neurotransmission in preclinical models, offering potential therapeutic insights for anxiety and cognitive enhancement with enhanced blood-brain barrier penetration properties. Phenibut has been clinically used in Russia, Ukraine, Belarus and other countries since the 1960s for treating anxiety disorders, insomnia, post-traumatic stress disorder, depression, vestibular disorders, asthenia, and stuttering, demonstrating historical therapeutic relevance for anxiety, sleep, and stress disorders. Phenibut was first developed in the Soviet Union by Soviet scientists for space physicians to help cosmonauts cope with stress, confirming specific therapeutic application for stress management and CNS protection. The hydrochloride salt form provides enhanced stability and solubility compared to free acid form, with the ready-to-use solution eliminating preparation time and ensuring precise dosing accuracy for in vivo animal studies.

Handling & Storage Guidelines

• Long-Term Storage: Store at room temperature, tightly sealed, away from heat, light and moisture; store in a cool and dry place. Formulated and packaged to prevent evaporation in storage; glass bottle with UV resistance minimizes degradation; keep tightly sealed; tamper-proof seal ensures safety in transit

• Solubility: Pre-dissolved in PEG400 vehicle – ready for direct use; Soluble in Water, PEG400, DMSO (Slightly); DMSO: 27.5 mg/mL (127.5 mM), sonication recommended; shake/agitate bottle before each administration for consistency

• Appearance: Red Color Liquid; 30mL volume containing 3000mg total Phenibut HCl at 100mg/mL concentration in PEG400; less than 10% variance in concentration, guaranteeing consistency; includes graduated 1mL pipette for convenient measurement

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering.