N-Acetyl-Semax-Amidate – Spray
$49.99 – $112.49Price range: $49.99 through $112.49
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N-Acetyl-Semax-Amidate – Spray is a high-purity laboratory-grade research peptide supplied as a ready-to-use aqueous solution (15mL liquid solution in deionized water Type II), functioning as an advanced acetylated and amidated derivative of Semax—a synthetic heptapeptide analog of the ACTH(4-10) fragment (Met-Glu-His-Phe-Pro-Gly-Pro) with cognitive-enhancing, neuroprotective, BDNF upregulating, and dopamine-modulating properties that exhibits significantly increased duration, potency, metabolic stability, enhanced receptor affinity, extended half-life, and improved blood-brain barrier penetration compared to parent Semax, modulates brain-derived neurotrophic factor (BDNF) levels (stimulates central BDNF synthesis) affecting neuroplasticity and cognitive function, modulates dopamine affecting neurotransmitter levels (supports concentration and motivation), and is sometimes regarded as a more stable structural analogue preferred in long-term experiments, supplied for convenient nasal spray delivery, available in bottle with graduated spray mechanism for convenient measurement, available for fast, compliant shipping to all U.S. states and European countries.
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≥99% peptide-grade purity verified by LC-MS with public lot-coded certificates of analysis for absolute transparency
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Formulation contains N-Acetyl-Semax-Amidate peptide in liquid solution for ready-to-use convenience
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Bottle engineered for convenient nasal spray measurement and refrigerated storage at 4°C (Do NOT freeze)
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15mL total volume liquid solution; exceeds 99% pure quality guarantee
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N-Acetyl-Semax-Amidate – Spray
This premium laboratory-grade research peptide is supplied as a ready-to-use aqueous solution engineered for modern scientific investigations requiring precise neuropeptide pharmacology and cognitive/neuroprotection research. N-Acetyl-Semax-Amidate is an advanced, N-acetylated and C-terminally amidated derivative of Semax—a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) that encompasses the ACTH(4-10) fragment, functioning as a nootropic and neuroprotective peptide with cognitive-enhancing properties improving concentration, working memory, mental stamina, and learning speed without causing jitteriness, stress resilience support, neuroplasticity enhancement, BDNF upregulation (stimulates central BDNF synthesis) affecting neuroplasticity and cognitive function, dopamine modulation supporting concentration and motivation affecting neurotransmitter levels, anti-inflammatory effects, and significantly increased duration, potency, and metabolic stability with enhanced receptor affinity, extended half-life, and improved blood-brain barrier penetration compared to parent Semax, sometimes regarded as a more stable structural analogue preferred in long-term experiments or procedures, making it a valuable tool for in vitro/in vivo modeling of cognitive enhancement, neuroprotection, neurodegenerative diseases, stress resilience, burnout/brain fog, BDNF-mediated neuroplasticity, dopamine pathway modulation, and anti-inflammatory brain research.
All domestic orders ship directly from primary United States production facilities, ensuring rapid delivery to all 50 U.S. states. International orders to the UK and continental Europe are fulfilled through our dedicated United Kingdom shipping hub, enabling seamless, efficient customs clearance across European borders without delay.
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Lot-coded containers with publicly accessible third-party LC-MS lab reports verifying specification ≥99% peptide-grade purity for absolute transparency
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Formulation contains N-Acetyl-Semax-Amidate peptide in 15mL liquid solution to guarantee ready-to-use convenience and peptide integrity
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Bottle maintains peptide stability during transit and refrigerated storage at 4°C (Do NOT freeze)
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15mL total volume liquid solution; exceeds 99% pure quality guarantee
Technical Specifications & Chemical Profile
| Chemical Property | Specification Data |
|---|---|
| Product Name | N-Acetyl-Semax-Amidate – Spray |
| Common Synonyms | N-Acetyl Semax Amidate, Ac-Semax-Amidate, N-Acetyl Semax, Semax, Met-Glu-His-Phe-Pro-Gly-Pro-NH2, ACTH(4-10) analog, ACTH fragment analog, (Pro8,Gly9,Pro10)ACTH-(4-10), TP RKEPV-NH2, heptapeptide, neuropeptide, nootropic peptide, neuroprotective peptide, cognitive enhancer peptide |
| CAS Number | 2920938-90-3 |
| Molecular Formula | C₃₇H₅₁N₉O₁₀S |
| Molar Mass | 858.97 g/mol |
| Amino Acid Sequence | Met-Glu-His-Phe-Pro-Gly-Pro (N-acetylated at N-terminus, C-terminal amidation) |
| IUPAC Name | (2S)-1-[2-{[(2S)-1-[(2S)-2-{[2-{[(2S)-2-{[(2S)-2-amino-4-methylsulfanylbutanoyl]amino}-4-carboxybutanoyl]amino}-3-(1H-imidazol-5-yl)propanoyl]amino}-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino}acetyl]pyrrolidine-2-carboxylic acid |
| Chemical Structure | Ac-TPRKEPV-NH2 |
| Primary Target Mechanism | Advanced N-acetylated and C-terminally amidated derivative of Semax; synthetic analog of ACTH(4-10) fragment; heptapeptide; N-acetylation at N-terminus for metabolic stability; C-terminal amidation for enhanced receptor affinity and half-life; cognitive enhancer improving concentration, working memory, mental stamina, and learning speed without causing jitteriness; neuroprotective effects protecting neurons from damage/degeneration; nootropic peptide; BDNF upregulation (stimulates central BDNF synthesis) affecting neuroplasticity and cognitive function (necessary for function of retina, cholinergic and dopaminergic neurons, stimulates development of new nerve connections, prolongs lifespan of existing cells, plays important role in long-term memory formation and all brain activities associated with formation of new neurons including learning new movements or improving strength); dopamine modulation (supports concentration and motivation) affecting neurotransmitter levels; stress resilience support especially under stress; neuroplasticity enhancement; enhanced metabolic stability; significantly increased duration and potency; enhanced receptor affinity; extended half-life; improved blood-brain barrier penetration; anti-inflammatory effects; sometimes regarded as more stable structural analogue preferred in long-term experiments or procedures; enhances learning and memory abilities; enhances melanocortin receptor activity in nervous system; makes thought processes run more fluidly; concentration lasts significantly longer; powerful tool for cognitive endurance; user reports indicate brightens mood while calming down; non-sedating and non-addictive; no tolerance or withdrawal; used for research in neuroprotection and cognitive function; used for research of biochemical studies, neurogenic, neuroregulatory, and neurorestorative biological processes |
| Physical Form | Liquid solution; clear liquid |
| Purity | ≥99% Pure (Validated by LC-MS) |
| Liquid Availability | 15mL liquid solution |
| Storage Condition | Store cold, keep refrigerated at 4°C; Do NOT freeze |
Research Applications & Storage Protocols
N-Acetylated and Amidated Semax Analog with BDNF Upregulation and Dopamine Modulation Profile
N-Acetyl-Semax-Amidate functions as an advanced, N-acetylated and C-terminally amidated derivative of Semax—a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) that encompasses the ACTH(4-10) fragment, with N-acetylation at N-terminus for metabolic stability and C-terminal amidation for enhanced receptor affinity and half-life. The peptide demonstrates cognitive-enhancing properties improving concentration, working memory, mental stamina, and learning speed without causing jitteriness, makes thought processes run more fluidly and concentration lasts significantly longer as powerful tool for cognitive endurance, exhibits neuroprotective effects protecting neurons from damage or degeneration, serves as nootropic peptide, upregulates brain-derived neurotrophic factor (BDNF) stimulating central BDNF synthesis affecting neuroplasticity and cognitive function (BDNF is peptide secreted by neurons necessary for function of retina hence effect of greater contrast and sharper vision after nootropic substances, cholinergic and dopaminergic neurons, its presence stimulates development of new nerve connections and prolongs lifespan of existing cells, plays important role in formation of long-term memory and in all brain activities associated with formation of new neurons including learning new movements or improving strength), modulates dopamine supporting concentration and motivation affecting neurotransmitter levels, provides stress resilience support especially under stress, enhances neuroplasticity, demonstrates enhanced metabolic stability with significantly increased duration, potency, enhanced receptor affinity, extended half-life, and improved blood-brain barrier penetration compared to parent Semax, has anti-inflammatory effects, is sometimes regarded as more stable structural analogue preferred in long-term experiments or procedures, enhances learning and memory abilities, enhances melanocortin receptor activity in nervous system, user reports indicate brightens mood while calming down, making it valuable for investigators studying cognitive endurance, cognitive enhancement, neuroprotection, neurodegenerative diseases, stress resilience, burnout/brain fog, memory and working memory mechanisms, BDNF-mediated neuroplasticity, dopamine pathway modulation, anti-inflammatory brain research, attention and focus improvement, learning speed, mental performance, and neuropeptide pharmacology in in vitro and in vivo experimental models.
Handling & Storage Guidelines
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Long-Term Storage: Store in refrigerator at 4°C, keep refrigerated, tightly sealed, away from heat, light and moisture; peptide solution requires refrigeration to remain stable; Do NOT freeze
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Solubility: Supplied as 15mL pre-dissolved liquid solution; ready-to-use; clear liquid appearance
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Administration (Research): Intranasal (preferred via nasal spray); spray bottle included for convenient measurement
Global Logistics & Order Fulfillment
We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.
Laboratory Use Only Disclaimer
This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please familiarize yourself with our Terms & Conditions prior to ordering. N-Acetyl Semax Amidate is not approved by the FDA and is sold strictly for scientific research use only. It is not intended for human or veterinary use. Always consult with a healthcare professional before starting any new supplement or research product.
| Strength |
10 mg ,30 mg |
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