Tropisetron HCl – Powder, 1g

Tropisetron HCl – 1g Powder

This premium laboratory-grade research compound delivers ultra-pure raw powder form with ≥98% purity verified by HPLC analytical testing. Tropisetron HCl represents a potent and selective serotonin 3 (5-hydroxytryptamine3; 5-HT3) receptor antagonist with antiemetic properties, offering technical value to modern scientific investigators studying nausea and vomiting suppression, fibromyalgia analgesia, cognitive enhancement, memory improvement, and 5-HT₃ receptor modulation in in vitro/in vivo modeling research application.

We proudly fulfill all U.S. orders directly from primary United States production facilities for domestic speed, while European and international orders utilize our dedicated United Kingdom shipping hub to ensure seamless, efficient customs clearance across the UK and continental Europe throughout all 50 U.S. states and European countries.

• Lot-coded material with public third-party lab reports providing absolute transparency for every batch

• Zero adulterants, excipients, or flow agents guarantee raw chemical purity for investigators

• Precision over-weighing compensates for natural adhesion loss during laboratory transfer procedures

• Sterile-sealed vial with tamper-proof seal engineered for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

5-HT₃ Receptor Antagonist & Antiemetic Activity Profile

Tropisetron is a potent and selective 5-HT3 receptor antagonist used mainly as an antiemetic to treat nausea and vomiting following chemotherapy, although it has been used experimentally as an analgesic in cases of fibromyalgia. It was patented in 1982 and approved for medical use in 1992. Tropisetron is a therapeutic alternative on the World Health Organization’s List of Essential Medicines. It is sold by Novartis in Europe, Australia, New Zealand, Japan, South Korea and the Philippines as Navoban, but is not available in the US. Tropisetron acts as both a selective 5-HT3 receptor antagonist and α7-nicotinic receptor partial agonist. The antiemetic properties are probably mediated via antagonism of receptors both at peripheral sites and in the central nervous system. Formulations containing tropisetron have been used in the treatment of nausea and vomiting associated with chemotherapy and for prevention of post-operative nausea and vomiting. Tropisetron is a well-tolerated drug with few side effects. Headache, constipation, and dizziness are the most commonly reported side effects associated with its use for in vitro/in vivo modeling applications.

Handling & Storage Guidelines

• Long-Term Storage: Store at 2-8°C (refrigerated); maintain inert atmosphere; keep vessel tightly sealed to prevent moisture absorption; store in cool and dry place

• Solubility: Water solubility 1.33 mg/mL; logP 3.14; suitable for analytical testing and research application

• Appearance: White crystalline solid, powder form

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.