LGD-3303 – Solution, 300mg (10mg/mL)

LGD-3303 – Solution, 300mg (10mg/mL)

This premium, laboratory-grade research compound delivers ultra-pure LGD-3303 solution at 10mg/mL concentration, representing the highest standard for modern scientific investigations into selective androgen receptor modulation and anabolic signaling mechanisms in muscle and bone. The ready-to-use solution format eliminates preparation time and ensures precise dosing accuracy for in vivo animal studies, providing investigators with a validated vehicle system ideal for analytical testing, pharmacokinetic modeling, and in vivo preclinical research applications where precise LGD-3303 administration is critical for studying muscle hypertrophy, bone density enhancement, and tissue-selective androgenic effects.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

• Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

• Formulation contains zero adulterants, excipients, flow agents, or contaminants—pure LGD-3303 solution only

• Strategic over-fill compensates for solution adhesion loss, guaranteeing minimum 30mL (300mg) recoverable volume

• Amber glass bottle features UV-resistant construction and tamper-proof seal for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

SARM-Mediated AR Agonism & Muscle/Bone Enhancement Profiling

LGD-3303 (LGD3303, LGD3, LG-3) functions as a drug which acts as a selective androgen receptor modulator (SARM), with good oral bioavailability, designed to selectively activate the androgen receptor (AR) signaling pathway in muscle and other tissues, aiming to maintain anabolic (muscle-building) effects. The compound is a selective agonist for the androgen receptor, producing functional selectivity with effective dissociation of anabolic and androgenic effects, acting as a partial agonist for androgenic effects, but a full agonist for anabolic effects. In vivo studies have shown that LGD-3303 supports the preservation of lean body mass and enhances skeletal parameters, including bone mineral density, demonstrating tissue-selective anabolic activity. Research has proven LGD-3303’s ability to increase muscle hypertrophy and bone density by connecting to specific muscle tissue, while also stimulating lipolysis (fat breakdown) and increasing nitrogen retention while reducing water retention. The compound has been investigated as a possible treatment for osteoporosis, and was shown in animal studies to enhance the effectiveness of a bisphosphonate drug, demonstrating therapeutic potential for bone density enhancement. Tissue-selective activity was maintained when LGD-3303 was dosed orally or by continuous infusion, two routes of administration with markedly different time versus exposure profiles, confirming its versatility for different research applications. LGD-3303 has potent activity on levator ani muscle but is a partial agonist on the preputial gland and ventral prostate, and never stimulated ventral prostate above intact levels despite increasing plasma concentrations of compound, demonstrating its selective androgenic profile with minimal androgenic side effects. LGD-3303 shows potential to increase muscle mass with minimal side effects, doesn’t negatively impact androgenic organs (such as prostate), prevents muscle wasting, works well as a standalone agent or stacked with other SARMS, and delivers great results in every aspect for different types of goals. This SARM mechanism positions LGD-3303 solution as a critical tool compound for investigating muscle hypertrophy research, bone density enhancement models, osteoporosis treatment studies, lipolysis mechanisms, nitrogen retention pathways, muscle wasting prevention, and tissue-selective androgen receptor signaling in preclinical models, offering potential therapeutic insights for metabolic and musculoskeletal disorders.

Handling & Storage Guidelines

• Long-Term Storage: Store at -20°C (-4°F) in a sealed container, away from light and moisture to maintain potency and maximize shelf life (up to 2 years). UV-resistant glass bottle minimizes degradation; tamper-proof seal ensures secure delivery. Avoid excessive heat and moisture; do not recommend long-term storage for solutions—use promptly after opening

• Solubility: Pre-dissolved formulation ready for direct use; Soluble in PEG400; Soluble in Ethanol at 0.0068 mg/mL rate; Soluble in DMSO; Water solubility low; for in vivo studies: 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline formulation recommended; shake/agitate bottle before each administration for consistency

• Appearance: Clear colorless to pale yellow liquid solution; 30mL volume containing 300mg total LGD-3303 at 10mg/mL concentration; <5% concentration variance for consistency

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.