LGD-3303 – Powder, 1g

LGD-3303 – Powder, 1g

This premium, laboratory-grade research compound delivers ultra-pure raw LGD-3303 powder at ≥98% purity, representing the highest standard for modern scientific investigations into selective androgen receptor modulation and anabolic signaling mechanisms in muscle and bone. The lyophilized crystalline powder form provides investigators with a single-compound reference standard ideal for analytical testing, in vitro cell culture modeling of AR-mediated pathways, and in vivo preclinical research applications where precise LGD-3303 isolation is critical for studying muscle hypertrophy, bone density enhancement, and tissue-selective androgenic effects.

All shipments to the 50 United States are fulfilled directly from primary U.S. production facilities, ensuring 2-5 business day delivery nationwide. International orders to the United Kingdom and continental Europe are processed through our dedicated United Kingdom shipping hub, which streamlines customs clearance and reduces transit times across all European countries. This dual-hub logistics infrastructure guarantees seamless, compliant delivery while maintaining chemical integrity throughout transit.

• Public third-party lab reports with unique lot-coding ensure absolute transparency for every batch sold

• Formulation contains zero adulterants, excipients, flow agents, or contaminants—pure LGD-3303 only

• Strategic over-weighing compensates for powder adhesion loss, guaranteeing minimum 1g recoverable material

• PET single-wall jar features UV-resistant construction and tamper-proof seal for transit safety

Technical Specifications & Chemical Profile

Research Applications & Storage Protocols

SARM-Mediated AR Agonism & Muscle/Bone Enhancement Profiling

LGD-3303 (LGD3303, LGD3, LG-3) functions as an orally active, nonsteroidal selective androgen receptor modulator (SARM) with high affinity for the androgen receptor, exhibiting a Ki of 0.9 nM, representing a more recent development from Ligand Pharmaceutical that improves upon the well-known SARM LGD-4033. The compound is a selective agonist for the androgen receptor, producing functional selectivity with effective dissociation of anabolic and androgenic effects, acting as a partial agonist for androgenic effects but a full agonist for anabolic effects, demonstrating good oral bioavailability. Research has proven LGD-3303’s ability to increase muscle hypertrophy and bone density by connecting to specific muscle tissue, while also stimulating lipolysis (fat breakdown) and increasing nitrogen retention while reducing water retention, making it effective for muscle growth and fat loss. The compound has been investigated as a possible treatment for osteoporosis and was shown in animal studies to enhance the effectiveness of bisphosphonate drugs, demonstrating therapeutic potential for bone density enhancement. LGD-3303 shows potential to increase muscle mass with minimal side effects, doesn’t negatively impact androgenic organs (such as prostate), prevents muscle wasting, works well as a standalone agent or stacked with other SARMS, and delivers great results in every aspect for different types of goals. The compound binds to androgen receptors specifically in muscle tissue, connecting to specific muscle tissue while in use, which explains its muscle hypertrophy and bone density benefits. This SARM mechanism positions LGD-3303 as a critical tool compound for investigating muscle hypertrophy research, bone density enhancement models, osteoporosis treatment studies, lipolysis mechanisms, nitrogen retention pathways, muscle wasting prevention, and tissue-selective androgen receptor signaling in preclinical models, offering potential therapeutic insights for metabolic and musculoskeletal disorders.

Handling & Storage Guidelines

• Long-Term Storage: Store at -20°C (-4°F) for optimal stability (up to 2 years); stable at room temperature for short-term storage. Minimize open air exposure; store in a cool, dry place in airtight conditions; protect from light and moisture; double-sealed Mylar bag provides moisture barrier and UV resistance

• Solubility: Soluble in PEG400; soluble in Ethanol at 0.0068 mg/mL rate; soluble in DMSO; water solubility low; for in vivo studies: 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline formulation recommended

• Appearance: Pale yellow fine crystalline powder; clear solutions in PEG400, ethanol, and DMSO when properly dissolved

Global Logistics & Order Fulfillment

We proudly support scientific advancement across all 50 U.S. states and throughout Europe. Customers can seamlessly toggle their preferred currency between USD and EUR using the currency switcher located on the left-hand side of our website. All shipments are securely packaged to withstand international transit without compromising structural or chemical stability.

Laboratory Use Only Disclaimer

This material is sold strictly for laboratory research and development use only. It is not approved for human consumption, nor for medical, veterinary, or household applications. All purchases are governed by our standard Terms & Conditions. Please review them carefully before placing your order.